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β β-Catenin Mouse Monoclonal Antibody(13C6)
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β β-Catenin Mouse Monoclonal Antibody(13C6) |
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Catalog |
XHY088M |
XHY088L |
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Quantity |
50µL |
100µL |
For research use only.
Applications: WB,IHC
Species Cross-Reactivity: H,M,R
Molecular Weight: ~92KD
Isotype: IgG1
Storage Buffer & Condition: PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Store : -20°C. Do not aliquot the antibody.
Recommended dilutions: WB: 1:1,000 IHC: 1:200
Optimal dilutions should be determined by the end user.
Specificity: The β-Catenin Mouse Monoclonal antibody detects endogenous β-Catenin proteins.
Background: The distinct peripheral cytosolic proteins, alpha, beta and gamma catenin (102, 94 and 86 kDa)
are found in many tissues and bind to the conserved cytoplasmic tail domain of the cell adhesion cadherins.
Catenins link E cadherin to other integral membrane or cytoplasmic proteins and are modulated by Wnt1
proto oncogene. The central core region of beta catenin is involved in mediation of cadherin catenin complex
interaction with EGFR. Beta-Catenin-mediated signalling is involved at several stages of vertebrate neural
development .
Applications:WB-Western blot IHC-Immunochemistry IF-Immunofluorescence IP-Immunoprecipitation
ChIP-Chormatin Immunoprecipitation
Reactivity: H-Human R-Rat M-Mouse Mk-Monkey Dg-Dog Ch-Chicken Hm-Hamster Rb-Rabbit Sh-Sheep