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CD21 Mouse Monoclonal Antibody(2C5)
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CD21 Mouse Monoclonal Antibody(2C5) |
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Catalog |
XHY083M |
XHY083L |
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Quantity |
50µL |
100µL |
For research use only.
Applications: IHC
Species Cross-Reactivity: H,M,R
Molecular Weight: ~113KD
Isotype: IgG1
Storage Buffer & Condition: PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Store : -20°C. Do not aliquot the antibody.
Recommended dilutions: IHC: 1:200
Optimal dilutions should be determined by the end user.
Specificity: The CD21 antibody detects endogenous CD21 proteins.
Background: CD21 also known as complement receptor 2 (CR2), C3d receptor or EBV receptor is a 140 kDa
protein. CD21 is a glycosylated type I transmembrane protein consisting of an extracellular face of a series
of 15 or 16 CCP domains. CD21 is the receptor for complement components C3d and iC3b as well as the
Epstein-Barr virus (EBV) glycoprotein gp350/220. The soluble CD21 (sCD21) was shown to efficiently trigger
CD23 signalling pathways in human monocytes. By inducing release of proinflammatory cytokines and
upregulating expression of molecules involved in antigen presentation, sCD21 modulates critical
monocyte functions that may be relevant to allergic and inflammatory disorders.
Applications:WB-Western blot IHC-Immunochemistry IF-Immunofluorescence IP-Immunoprecipitation
ChIP-Chormatin Immunoprecipitation
Reactivity: H-Human R-Rat M-Mouse Mk-Monkey Dg-Dog Ch-Chicken Hm-Hamster Rb-Rabbit Sh-Sheep