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For research use only.

Applications: WB

Species Cross-Reactivity: H   

Molecular Weight: ~35KDa

Isotype: IgG

Storage Buffer & Condition: PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

Store : -20°C. Do not aliquot the antibody.

Recommended dilutions: WB: 1:2,000

Optimal dilutions should be determined by the end user.

Specificity: MeCP2 antibody detects endogenous MeCP2 proteins 

Background: Methyl-CpG-binding protein 2(MeCP2), whose exact function is unclear. It appears to help

regulate gene activity (expression) by modifying chromatin, the complex of DNA and protein that packages

DNA into chromosomes. The MeCP2 protein usually regulates genes involved in brain function, even though

this protein is found throughout the body.Within the brain, the MeCP2 protein is important for the function

of nerve cells (neurons) and is present in high levels in mature neurons. This protein likely plays a role in

maintaining connections (synapses) between neurons, where cell-to-cell communication occurs. Many of the

genes that are known to be regulated by the MeCP2 protein play a role in normal brain function,

particularly the maintenance of synapses.

Applications:WB-Western blot   IHC-Immunochemistry   IF-Immunofluorescence   IP-Immunoprecipitation

                            ChIP-Chormatin Immunoprecipitation

Reactivity:   H-Human R-Rat M-Mouse Mk-Monkey Dg-Dog Ch-Chicken Hm-Hamster Rb-Rabbit Sh-Sheep