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Bcl-2 Mouse Monoclonal Antibody(6B5)
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Bcl-2 Mouse Monoclonal Antibody(6B5) |
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Catalog |
XHY061M |
XHY061L |
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Quantity |
50µL |
100µL |
For research use only.
Applications: WB, IHC
Species Cross-Reactivity: H, R, M
Molecular Weight: 26KDa
Isotype: IgG1
Storage Buffer & Condition: PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Store : -20°C. Do not aliquot the antibody.
Recommended dilutions: WB: 1:1,000~2,000 IHC: 1:200
Optimal dilutions should be determined by the end user.
Specificity: Bcl-2 antibody detects endogenous Bcl-2 proteins
Background: BCL2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of
some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2
to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. BCL2 suppresses apoptosis in
a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. It regulates cell
death by controlling the mitochondrial membrane permeability.
Applications:WB-Western blot IHC-Immunochemistry IF-Immunofluorescence IP-Immunoprecipitation
ChIP-Chormatin Immunoprecipitation
Reactivity: H-Human R-Rat M-Mouse Mk-Monkey Dg-Dog Ch-Chicken Hm-Hamster Rb-Rabbit Sh-Sheep